What Is Celecoxib and When Is It Used?

Celecoxib is a prescription anti-inflammatory drug that belongs to the COX‑2 inhibitor family. It’s most often prescribed for arthritis, back pain, and other joint problems where swelling and pain are a big hassle.

Unlike older NSAIDs, celecoxib aims to spare your stomach lining while still cutting down inflammation. That’s why many doctors pick it for people who can’t tolerate regular ibuprofen or naproxen.

How to Take Celecoxib Correctly

Typical adult dosing starts at 200 mg once daily for mild pain, but many doctors go up to 400 mg daily for more severe arthritis. Split the dose into 200 mg twice a day if your doctor recommends it. Always swallow the capsules whole with a glass of water; don’t crush them.

Take it with food if you notice stomach upset, though it’s designed to be gentler on the gut. If you miss a dose, take it as soon as you remember—unless it’s almost time for your next dose, then just skip the missed one and continue your schedule.

Common Side Effects and Safety Checks

Most people tolerate celecoxib well, but be on the lookout for headaches, dizziness, or mild stomach discomfort. Serious side effects are rare but can include high blood pressure, swelling of the legs, or heart‑related issues. If you have a history of heart disease, talk to your doctor before starting.

Blood thinners, certain antidepressants, and other NSAIDs can interact with celecoxib, raising the risk of bleeding or kidney problems. Always list every medication and supplement you take when you discuss celecoxib with your prescriber.

Pregnant or nursing moms should avoid celecoxib unless a doctor says it’s absolutely necessary.

Before you order, check your kidney and liver function labs if you’ve had any problems before—your doctor may want a fresh set of results.

In short, celecoxib works best when you follow the prescribed dose, watch for warning signs, and keep your doctor in the loop about other meds you’re using.